Cholecalciferol

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  Vitamin D3 (Cholecalciferol)

  Vitamin D3 (cholecalciferol) is a pre-hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. Vitamin D3 is metabolized into a potent steroid hormone called calcitriol, More recently, it has become clear that receptors for calcitriol, are present in a wide variety of cells, and that calcitriol, has biologic effects which extend far beyond control of mineral metabolism.It is believed that vitamin D3 and its metabolites, play an important part in the regulation of genes involved in cell growth, differentiation and proliferation. By promoting differentiation and inhibiting proliferation, vitamin D may become an important factor in cancer prevention and therapy. Through its regulation of genes, calcitriol controls the production of immune factors known as lymphokines, which effect cell-mediated immunity functions.

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  Vitamin D3 Dosage

  Vitamin D3 is a very powerful protection against infection of any kind. Our body makes the precursor to D3 while we are lying in the sun or just running around in our bathing suits. In 20 minutes our body makes about 20000 IU of vitamin D3. In an hour of full body exposure, we would have 80000 IU in 4 hours, 320000 IU and so on. 20000 IU of D3 equates to 0.5 mg of D3 (one half milligram). The bottles in the stores tell us that 400 IU is our DV. It makes us think that this should be sufficient. Most of us don't even know what DV means. We see comments on the internet, in articles, in books and in the media about vitamin D toxicity. They scare us into thinking that we better not take too much. But what is too much? If our body can make 20000 IU in just 20 minutes and even more if we stay in the sun longer, how much is too much? Vitamin D3 is made in three steps or three different processes. 1.The skin makes cholecalciferol (a precursor to D3) in the 5th layer of the skin (stratum basale). 2.From there it goes through the blood to the liver where it is converted into calcidiol, a prohormone. 3.It really doesn't become active until it is converted one more time into calcitriol which is the active steroid hormone that controls the uptake of calcium and performs many other functions in the body. And the body makes that itself when it needs it. The process is self regulatory. The stored calcidiol just stays in the blood or in the fatty tissue until it is needed by the body. Then ...

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