Oxaliplatin
Chemotherapeutic Drug
Bowel cancer victims denied life saving treatment available in Europe...for use on the NHS. Avastin (bevacizumab), which costs about GBP1,800 a month, has been shown to shrink bowel tumours in 78 per cent of patients when it is added to chemotherapy drugs capecitabine and oxaliplatin. This could make them... In this article: Cancer, Bevacizumab, Europe, Oxaliplatin, Department of Health, UK, Surgery, and Capecitabine |
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Telegraph.co.uk - UK news | 5 days ago
Bowel cancer drug rejected by Nice
...some 6,000 people a year in the UK. Pharmaceutical giant Roche offered a patient access scheme to reduce the cost of Avastin, which would have seen a cap on its cost at 12 months and free oxaliplatin. Roche said this would have reduced the...
In this article: Cancer, Bevacizumab, UK, Department of Health, Surgery, and Capecitabine
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MedicineNet | 6 days ago
Combo Treatment Beneficial in Biliary-Tract Cancer Study
...drugs intravenously (bevacizumab at 10 milligrams per kilogram, followed by gemcitabine at 1,000 milligrams per square meter, and oxaliplatin at 85 milligrams per square meter) on days 1 and 15, every 28 days. Whole-body PET scans were...
In this article: Cancer, Gemcitabine, Bevacizumab, and Peripheral neuropathy
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Philly.com | November 03, 2009
Teva says Barr gave boost to 3Q profit
...the Israeli company. Teva's North American sales rose 33 percent to $2.23 billion due to the introduction of a generic version of Ortho Tri-Cyclen birth control and a generic version of the cancer treatment Eloxatin. Other generic drugs...
In this article: Teva Pharmaceutical Industries Ltd., Thomson Reuters, Legal age, Eloxatin, Lotrel, Cancer, Multiple sclerosis, Copaxone, and North Wales
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Medical News Today | October 27, 2009
Clinical Trial Promotes New Standards For Colorectal Cancer Treatment
...the way we run clinical trials in cancer patients." Based on the trial the US Food and Drug Administration approved a new agent, oxaliplatin, administered with 5-fluorouracil for the indication "treatment of previously untreated...
In this article: Cancer, Pharmacia, Canada, U.S., Medical advice, Surgery, and 5-fluorouracil
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Medical News Today | November 18, 2009
Poniard Pharmaceuticals Announces Updated Positive Clinical Data From Phase 2 Trial Of Picoplatin In Colorectal Cancer
...development. "Our updated proof-of-concept Phase 2 safety and efficacy results continue to suggest that picoplatin could be superior to oxaliplatin as a neuropathy-sparing alternative when used in combination as a first-line treatment for...
In this article: Cancer, Platinum, Neuropathy, 5-fluorouracil, FDA, Medical advice, and Thrombocytopenia
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Wikipedia | August 23, 2009
Oxaliplatin
...known as FOLFOX for the treatment of colorectal cancer. Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin or by Medac GmbH under the trademark Oxaliplatin Medac. There are generic equivalents on the market now
In this article: Cancer, Platinum, Fluorouracil, Trademark, Cisplatin, Carboplatin, U.S. Food and Drug Administration, Sanofi-Aventis, and Folinic acid
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Philly.com | September 14, 2009
Appeals court reverses approval for Teva, others
...colon cancer. The appeals court ruling Thursday sends the case back to U.S. District Court for further consideration on Eloxatin, which generated annual U.S. sales of more than $1.3 billion last year for the French company. Israeli-based...
In this article: Sanofi-Aventis, U.S., Legal age, Sanofi pasteur, Eloxatin, Cancer, Teva Pharmaceutical Industries Ltd., and U.S. Food and Drug Administration
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Medical News Today | August 18, 2009
Vectibix(R) Significantly Improved Progression-Free Survival In Second-Line Treatment Of KRAS Wild-Type Metastatic Colorectal Cancer
...showed that Vectibix significantly improved progression-free survival in mCRC patients with KRAS wild-type tumors in combination with FOLFOX (an oxaliplatin-based chemotherapy). Detailed efficacy and safety data from both studies will be...
In this article: KRAS, Vectibix, Cancer, Amgen, FDA, Irinotecan, Chemotherapy regimens, Medical advice, SEC, and Joint venture
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Centre Daily Times | November 19, 2009
Enzon Presents Data at 2009 EORTC Meeting
...the duration of their prior therapy. EZN-2208 is being evaluated in a Phase 2 study in patients with metastatic colorectal cancer who failed prior oxaliplatin and irinotecan containing regimens (CRC). EZN-3042, a novel survivin messenger...
In this article: Cancer, Oligonucleotide, Irinotecan, Androgen, Revenue, Locked nucleic acid, G-CSF, and Docetaxel
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Description from Wikipedia:
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility.
Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin or by Medac GmbH under the trademark Oxaliplatin Medac.
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