Gonadotropin-releasing hormone
Gonadotropin-releasing hormone
...understood. For instance, there is likely to be a role for GnRH1 in the placenta and in the gonads. GnRH and GnRH receptors are also found in cancers of the breast, ovary, prostate and...
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Gonadotropin-releasing hormone analogue
...after the human hypothalamic gonadotropin-releasing hormone (GnRH). A GnRH analogue is designed to interact with the GnRH receptor and modify the release of pituitary gonadotropins FSH...
Fertility medication
...releasing hormone, Estrogen antagonists or Gonadotropins. Either Gonadotropin-releasing hormone (GnRH) itself or any of its agonists (i.e. Lupron) may be used. GnRH releases...
Buserelin
...is a Gonadotropin-releasing hormone agonist (GnRH agonist). By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and...
Gonadotropin-releasing hormone antagonist
...are made up multiple, often synthetically produced amino acids. GnRH antagonists compete with natural GnRH for binding to GnRH receptors, thus decreasing or blocking GnRH action in the...
"We know stress affects the top-tier reproductive hormone, GnRH, but we show, in fact, that stress also affects another high-level hormone, GnIH, to cause reproductive dysfunction," said lead author Elizabeth Kirby, a graduate student at UC Berkeley's Helen Wills Neuroscience Institute. "This work provides a new target for researchers, a new way to think about infertility and dysfunction. The more we know, the more we can look for ways to treat it."
Stress Puts Double Whammy On Reproductive System, Fertility ScienceDaily: Latest Science News | 8 months ago
Hypothalamic-pituitary-gonadal axis
...the gonads produce estrogen and testosterone. The hypothalamus is located in the brain and secretes GnRH. GnRH travels down the anterior portion of the pituitary via the hypophyseal...
Kallmann syndrome
Females are treated with estrogen and progestins. To induce fertility in males or females, GnRH (aka LHRH) is administered by an infusion pump, or hCG/hMG/FSH/LH combinations are...
Neurocrine Announces Top-Line Results From 703 Study (Tulip PETAL Study) of Elagolix for Treatment of Endometriosis Pain
...fifth Phase 2 clinical trial using its proprietary, orally-active nonpeptide Gonadotropin-Releasing Hormone (GnRH) receptor antagonist, elagolix, in patients with endometriosis. "The...
Degarelix (FIRMAGON(R)) Vs Leuprolide (Lupron Depot(R)) In Patients With Advanced Prostate Cancer: Further Analysis From A Phase III Pivotal Trial
...with 96.4% for leuprolide. About FIRMAGON FIRMAGON is an injectable gonadotropin-releasing hormone (GnRH) receptor antagonist approved by the U.S. Food and Drug Administration...
AEterna Zentaris Announces Positive Results For Phase 2 Study With LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 In Endometrial Cancer
...entitled, "The antitumoral activity and safety of AEZS-108 (AN-152), a LHRH agonist linked doxorubicin in women with LHRH-receptor positive gynaecological tumors", patients with...
Degarelix: A New Approach For The Treatment Of Prostate Cancer
...are a new class of agent that act via immediate and competitive blockade of pituitary GnRH receptors. GnRH blockers directly block the release of luteinizing hormone and...
