Glutathione
Peptide
Acetaminophen-Related Liver Damage May Be Prevented By Common Herbal Medicine...this byproduct is easily deactivated when it binds to a naturally occurring, protective molecule called glutathione. But the body's glutathione stores are finite, and are quickly depleted when the recommended doses of acetaminophen are... In this article: Acetaminophen, Glutathione, S-Methylmethionine, Liver transplantation, Medical advice, Peptic ulcer, Nausea, and Methionine |
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Medical News Today | 4 days ago
Heart Disease Outcomes Predicted By Marker Of Oxidative Stress
Smoking and alcohol consumption are also linked with higher levels of oxidized cysteine. Cysteine is itself a short-lived precursor to glutathione, one of the main antioxidants found inside cells, says Dean P. Jones, PhD, professor of...
In this article: Cystine, Cysteine, Emory University School of Medicine, Zinc, and Amino acid
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Centre Daily Times | 5 days ago
Novelos Therapeutics and Academic Collaborators Present Scientific Findings at International Cancer Conference
...'Our Products', 'NOV-002' section. Novelos Therapeutics, Inc. is a biopharmaceutical company commercializing oxidized glutathione-based compounds for the treatment of cancer and hepatitis. NOV-002, the lead compound currently in...
In this article: Cancer, Hepatitis, Lung cancer, Fast Track, and University of Miami Miller School of Medicine
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PR Newswire: Health / Biotech | November 13, 2009
Telik Announces Third Quarter 2009 Financial Results
...and inflammatory diseases. The company's most advanced investigational drug candidates in clinical development are TELINTRA®, a modified glutathione analog for the treatment of cytopenias due to myelodysplastic syndrome or chemotherapy,...
In this article: Trademark, Palo Alto, California, Cancer, Ovarian cancer, Myelodysplastic syndrome, Lung cancer, and Nasdaq
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Reuters | November 12, 2009
Acetaminophen could up asthma, wheezing risk
...suggested that more widespread acetaminophen use could be one contributing factor, given that the drug lowers levels of an antioxidant called glutathione found in lung tissue, FitzGerald and his team note in the journal CHEST. Also, the...
In this article: Asthma, Reuters Health, Acetaminophen, Fever, British Columbia, and NEW YORK
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EyeScience(TM) Announces New Program to Improve Patient Compliance and Practice Profits
...E, Zinc, Cooper, Selenium, Vitamin B-6, Folate, Lutein, Zeaxanthin, Omega-3, Bilberry, Alpha-Lipoic Acid, Grape seed Extract and L-Glutathione," says Dr. Michael A. Samuel, nationally renowned clinician, retina surgeon, researcher, and...
In this article: Vitamin, Trademark, Vitamin B-6, Vitamin E, Zinc, Magnesium, and Bilberry
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Chelation Therapy Drug Found Safe And Beneficial For Children With Autism
...or liver function. Of greatest interest was a surprising finding that DMSA therapy had a dramatic effect on glutathione levels. Glutathione is the body's primary defense against toxic metals, and it was very abnormal in children with...
In this article: Autism, Dimercaptosuccinic acid, Southwest College of Naturopathic Medicine, Medical advice, Lead poisoning, Autism Research Institute, and FDA
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Boing Boing | October 31, 2009
Anti-vaccine fear versus science
...a huge screen during his presentation. (If only it were that simple.) Others talked of the powers of enzymes, enemas, infrared saunas, glutathione drips, chelation therapy (the controversial -- and risky -- administration of certain chemicals...
In this article: Autism, Halloween, Vitamin D, B.F. Skinner, Enema, and Huffpo
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Life Extension(R) Introduces Glutathione, Cysteine & C Formulation With Setria(R) From Kyowa Hakko USA
...in 100 count bottles at http://www.lef.org/Vitamins-Supplements/Item00113/Glutathione-Cysteine-and-C.html. Glutathione (gamma-L-glutamyl-L-cysteinyl-glycine) is a peptide-like (short-protein) molecule synthesized in the body from the...
In this article: Cysteine, Amino acid, Methionine, NEW YORK, USA, Taurine, Branched-chain amino acids, and Antioxidant
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Novelos Therapeutics Announces $1 Million NIH Grant to MGH to Study NOV-002 and NOV-205 In Animal Models of Radiation-Induced Lung Injury
Novelos Therapeutics, Inc. is a biopharmaceutical company commercializing oxidized glutathione-based compounds for the treatment of cancer and hepatitis. NOV-002, the lead compound currently in...
In this article: National Institutes of Health, Hepatitis, Cancer, Anti-inflammatory, Breast cancer, and AIDS
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Groundbreaking Model Of Heart Disease Rewarded With NIH Pioneer Award
...tissue. To protect cells from free radicals, the body makes antioxidants. Benjamin's work focuses on a particular antioxidant, reduced glutathione, which is produced when a protein called alpha B-Crystallin unfolds inside of cells. When...
In this article: National Institutes of Health, Heart failure, University of Utah, Francis Collins, Medical advice, Oxygen, and Crystallin
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More on Glutathione
Description from Wikipedia:
Glutathione (GSH) is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione, an antioxidant, protects cells from toxins such as free radicals.
Thiol groups are kept in a reduced state at a concentration of approximately ~5 mM in animal cells. In effect, glutathione reduces any disulfide bond formed within cytoplasmic proteins to cysteines by acting as an electron donor. In the process, glutathione is converted to its oxidzed form glutathione disulfide (GSSG). Glutathione is found almost exclusively in its reduced form, since the enzyme that reverts it from its oxidized form, glutathione reductase, is constitutively active and inducible upon oxidative stress. In fact, the ratio of reduced glutathione to oxidized glutathione within cells is often used scientifically as a measure of cellular toxicity.
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