Lorenzo's Oil

...coming in from the cold. Two boys treated three years ago with a gene therapy for X-linked ALD, the brain disease featured in the film Lorenzo's Oil, fared so well that doctors have treated a third and are now looking for adult volunteers.

In this article: Cancer, Paris, France, UK, France, and US

..."bubble boy disease." That's a risk that specialists hope a lentivirus-based gene therapy will eliminate. Best known from the movie "Lorenzo's Oil", adrenoleukodystrophy, or ALD, is a rare genetic disease that, in its most devastating form,...

In this article: HIV, Lentivirus, University Paris, Leukemia, Dementia, Brain damage, Adrenoleukodystrophy, and AIDS

...or in adulthood. It progresses to death within 3-10 years of diagnosis. Many people became familiar with ALD from the 1992 movie Lorenzo's Oil, which featured a young boy affected with this disease. ALD is currently treated with allogeneic...

In this article: Adrenoleukodystrophy, Graft Versus Host Disease, Meningitis, National Institute of Health, and France

...cells degenerates. A result is progressive brain damage and death two to five years after diagnosis. The disease was the focus of the movie "Lorenzo's Oil." Scientists say they believe they avoided the cancer problem by using a different...

In this article: Leukemia, HIV, Cancer, and Cell Genesys

...the journal Science. The authors report that a novel gene therapy seems to stop progression of ALD, the rare disease featured in the movie Lorenzo's Oil. The study describes results from just two patients, and the therapy is not without...

In this article: Paris, Washington, Budapest, and Hungary

Navigation - link to other main sections from here Gene therapy could cure Lorenzo's Oil brain disease A devastating brain disease that kills boys by the time of adolescence has been stopped in its tracks by a gene therapy that raises...

In this article: Brain damage, Adrenoleukodystrophy, Lentivirus, and Paralysis

Lorenzo's Oil is an Academy Award-nominated 1992 drama film directed by George Miller . It is based on the true story of Augusto and Michaela Odone, two parents in a relentless search for a cure for their son Lorenzo 's adrenoleukodystrophy...

In this article: Adrenoleukodystrophy, Academy Awards, Fatty acid, Susan Sarandon, and Insulator

...that more than two years after gene therapy their brain disease has been arrested," he said. Featured in the 1992 movie "Lorenzo's Oil," ALD is a rare hereditary condition caused by a deficiency of a protein involved in fatty acid...

In this article: HIV, Leber congenital amaurosis, Leukemia, Dementia, X-linked adrenoleukodystrophy, Rare disease, Fatty acid degradation, and Severe combined immunodeficiency

...case in case a cure is found, the High Court was told. His situation was compared to the life of a boy in the Hollywood film Lorenzo's Oil. Staff at the hospital where the 13-month-old is being treated want to turn off the life...

In this article: King's College London, Congenital myasthenic syndrome, and Adrenoleukodystrophy

...nursed him 24/7 while she helped my father research the little-known disease that had struck down their son. The result of their study, Lorenzo's Oil, became a therapy used widely by boys afflicted with ALD - and the subject of a Hollywood...