HIV
Disease
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Ardea Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference...in advanced cancer patients. RDEA806, for the treatment of HIV, is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that has successfully completed a Phase 2a study in HIV patients. RDEA427, a next generation NNRTI, has... In this article: Piper Jaffray, Reverse transcriptase inhibitor, Cancer, HIV, Urat1, Private Securities Litigation Reform Act of 1995, Hyperuricemia, and Nasdaq |
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Rivals | November 18, 2009
World AIDS Day to create awareness in the South
...to the new generation," she said. Rahill said she doesn't see working to fight HIV as any different than fighting cancer or obesity, but that social attitudes make raising awareness of HIV more difficult. "The problem with HIV is that there...
In this article: AIDS, Student Union, World AIDS Day, IP Address, Cancer, Obesity, and University of Chicago
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scotsman.com - Politics | 5 days ago
Make cancer and Aids wonderdrug available on NHS, ministers told
...which, in turn, stimulates the immune system. This has reduced the activity of MS, while other doctors have used it to treat fertility problems as well as cancer and HIV/Aids. In America in 1981, Dr Ian Zagon conducted research and...
In this article: Cancer, AIDS, Endorphin, Crohn's disease, Naltrexone, and Morphine
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Prime Newswire | 4 days ago
Myriad Pharmaceuticals Inc. to Present at the 21st Annual Piper Jaffray Health Care Conference
Myriad Pharmaceuticals, Inc. is a pharmaceutical company focused on discovering, developing, and commercializing novel small molecule drugs that address severe medical conditions, including cancer and HIV infection. Our pipeline...
In this article: Piper Jaffray, Cancer, Melanoma, and HIV Infection
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Centre Daily Times | 5 days ago
Cytheris Announces Initiation of NCI/NIH-Sponsored Phase I/IIa Clinical Study of Tumor Vaccination and Interleukin-7 (IL-7) in Patients with High Risk Pediatric Solid Tumors
...and protect CD4+ and CD8+ T-cells. Currently, Cytheris is conducting multiple international investigations of IL-7 in HCV, HIV, cancer, with trials for other indications planned to initiate in 2H09. About Cytheris' Interleukin-7 Clinical...
In this article: IL-7, CD4, Cancer, National Institutes of Health, Bethesda, Maryland, Taiwan, and Italy
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washingtonpost.com | November 20, 2009
Report: 20-somethings can go 2 years between Paps
...ACOG had previously backed a two- to three-year wait. Women with HIV, other immune-weakening conditions or previous cervical abnormalities may need more frequent screening. Paps can spot pre-cancerous changes in the cervix in time to...
In this article: Human papillomavirus, Cervical cancer, Cancer, Breast cancer, American College of Obstetricians and Gynecologists, American Cancer Society, Washington, and U.S.
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Medical News Today | November 13, 2009
10 Ways To Reduce Cancer Risk
...blood, from contaminated needles or by having unprotected sex. Human immunodeficiency virus (HIV), the virus that causes AIDS, also increases the risk of several types of cancer. It's most commonly transmitted by unprotected sex or sharing of...
In this article: Cancer, Fruit, Breast cancer, Obesity, Lung cancer, Human papillomavirus, Hepatitis, Tobacco, and Revenue
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Science News From Weill Cornel: November 2009
...an immune response. Dr. Salvatore believes using an integrase-defective viral vector is a potentially safer method to create vaccines for the prevention of infectious diseases such as influenza, HIV, and even cancer. The researchers will...
In this article: Weill Cornell Medical College, Parkinson's disease, Cholesterol, National Institutes of Health, Low-density lipoprotein, Inflammation, Lentivirus, Influenza, and Atherosclerosis
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Description from Wikipedia:
Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that can lead to acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Previous names for the virus include human T-lymphotropic virus-III (HTLV-III), lymphadenopathy-associated virus (LAV), and AIDS-associated retrovirus (ARV).
Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unprotected sexual intercourse, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (Vertical transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world.
HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4 T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4 T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4 T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4 T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
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