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Genasense® Given as High-Dose IV Infusion with Chemotherapy Shows Promising Activity in Advanced Melanoma...Company is developing tesetaxel, a novel, orally absorbed, semi-synthetic taxane that is in the same class of drugs as paclitaxel and docetaxel. Genta intends to evaluate the clinical activity of tesetaxel in a range of human cancers. Ganite... |
Exome-Sequencing Might Help Identify Genetic Cause Of Thousands Of Disorders...malformation patterns found in Miller syndrome are similar to the birth defects in fetuses of some, but not all, mothers who took the drug methotrexate during pregnancy. Knowing this might provide some clues to genetic susceptibility to birth... |
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Reuters | 3 days ago
UPDATE 1-Roche says Actemra successful in study for sJIA
...that Actemra significantly halted the progression of joint damage in patients with rheumatoid arthritis for two years when combined with the common treatment methotrexate. [ID:nN16364143] Reporting by Katie Reid ; editing by John Stonestreet )
In this article: Actemra, Arthritis, Rheumatoid arthritis, Methotrexate, and Rash
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Medical News Today | 4 days ago
NeoPharm Presents The Phase I Data For Patients With Metastatic Solid Tumors
...Inc. (Other OTC : NEOL.PK) announced the results of a Phase I clinical trial of Liposome Encapsulated Docetaxel (LE-DT) an active component of Taxotere ® at a joint International Conference of the American Association for Cancer Research...
In this article: Cancer, Taxotere, Medical advice, Back pain, American Association for Cancer Research, Rigor, Rash, Peripheral edema, and Peripheral neuropathy
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Reuters | 5 days ago
Pregnancy outcomes good for women with MS
...and research suggests that at least one -- beta-interferon -- may be associated with miscarriage. Chakravarty noted that the drug methotrexate , sometimes used for MS, is known to cause birth defects. SOURCE: Neurology , online...
In this article: Neurology, C-section, Epilepsy, Methotrexate, Anti-inflammatory, Corticosteroid, Muscle weakness, and Multiple sclerosis
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Prime Newswire | 5 days ago
Threshold Pharmaceuticals Presents Interim Prostate Cancer Data From Early Stage Trials of TH-302
...three chemotherapeutic regimens being evaluated in combination with TH-302 which is given on days 1 and 8 of a three week docetaxel cycle. Docetaxel is administered at the full prescribed dose of 75 mg/m2. The maximum tolerated dose (MTD) of...
In this article: Cancer, Docetaxel, South Dakota, Oxygen, Doxorubicin, Soft tissue sarcoma, and Securities Exchange Commission
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Medical News Today | 6 days ago
Genentech Submits Supplemental Applications To FDA For Avastin Combined With Commonly Used Chemotherapies For Women With Advanced Breast Cancer
...trial, there was a 20.5 percent increase in severe to life-threatening and fatal side effects for Avastin plus paclitaxel chemotherapy vs. paclitaxel alone. Because mild side effects of Avastin plus paclitaxel were not studied, they are...
In this article: Bevacizumab, Breast cancer, Paclitaxel, FDA, Genentech, Surgery, Cancer, Taxane, HER2, and Capecitabine
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PR Newswire: Health / Biotech | 6 days ago
YM BIOSCIENCES REPORTS CYT997 ORAL VASCULAR DISRUPTING AGENT RESULTS PRESENTED AT AACR-NCI-EORTC MEETING
... CYT997 is able to produce potent vascular disrupting effects in tumors (colon adenocarcinoma xenograft model), and in combination with cisplatin dosed weekly leads to enhanced antitumor effects compared to cisplatin alone. Administration of...
In this article: Nimotuzumab, Cancer, Cisplatin, Adenocarcinoma, Dermatitis, and Rash
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Medical News Today | 6 days ago
ASCO Releases Updated Treatment Guidelines For Patients With Stage 4 Non-Small Cell Lung Cancer
...( Camptosar ), paclitaxel (Taxol ), pemetrexed (Alimta ) or vinorelbine (Navelbine ). - Bevacizumab (Avastin ) is recommended with carboplatin plus paclitaxel in particular circumstances. - Physicians may consider adding cetuximab...
In this article: Lung cancer, Cancer, Gefitinib, Erlotinib, Pemetrexed, Carboplatin, Paclitaxel, Irinotecan, and Gemcitabine
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Reuters | 6 days ago
UPDATE 1-Roche applies for Avastin advanced breast cancer use
...both demonstrated that Avastin plus commonly used chemotherapies -- taxane -based chemotherapy, anthracycline-based chemotherapy and capecitabine -- increased the time women lived without the disease growing or spreading, compared with using...
In this article: Avastin, Breast cancer, Genentech, Taxane, Capecitabine, and U.S. Food and Drug Administration
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MarketWatch.com - MarketPulse | 6 days ago
Roche unit files for 2 FDA clearances for Avastin
...received chemotherapy for advanced HER2 -negative breast cancer. The supplemental Biologics License Applications concern Avastin , generically bevacizumab , combined with two commonly used chemotherapies. One is docetaxel ; the other envisions...
In this article: Bevacizumab, FDA, Taxane, Capecitabine, Breast cancer, HER2, Docetaxel, Genentech, and MarketWatch
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Medical News Today | November 12, 2009
Landmark Study In The Lancet Oncology Shows Capecitabine ( Xeloda (R)) Combination Therapy Reduces Early Breast Cancer Recurrence
...three-year interim analysis of a randomised, prospective trial (known as FinXX) compared adjuvant capecitabine in combination with docetaxel and cyclophosphamide plus epirubicin for the treatment of early breast cancer with the standard,...
In this article: Capecitabine, Breast cancer, Cancer, Cyclophosphamide, Docetaxel, Fluorouracil, The Lancet, Finland, and Medical advice
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BBC News | November 10, 2009
Drug 'shrinks lung cancer tumour'
...on mice showed the drug was effective against tumour cells, both in isolation, and in combination with the standard chemotherapy agent, cisplatin. Dr Joanna Owens , of the charity Cancer Research UK , said: "It is encouraging to see...
In this article: Lung cancer, Fgf-2, Imperial College London, Growth hormone, Cancer Research, Surgery, Cisplatin, Cancer, and Cancer Research UK
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Prime Newswire | November 10, 2009
Genmab Announces Results for the Nine Months Period of 2009
...and not infringed by Arzerra. In October, we received accelerated approval for Arzerra from the FDA for CLL that is refractory to fludarabine and alemtuzumab. The FDA approval triggered a milestone payment of DKK 116 million from GSK.
In this article: Genmab A/S, GlaxoSmithKline, Revenue, Ofatumumab, FDA, Zalutumumab, NHL, Trademark, Rituximab, and US
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Medical News Today | November 10, 2009
Improved Recurrence-Free Survival With Capecitabine , But Increased Adverse Events
...risk early breast cancer participated in this randomized controlled trial. They were assigned to either three cycles of capecitabine and docetaxel followed by three cycles of cyclophosphamide , epirubicin, and capecitabine (capecitabine...
In this article: Capecitabine, Breast cancer, Cancer, Cyclophosphamide, Docetaxel, Fever, Medical advice, Taxane, Fluorouracil, and Finland
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Centre Daily Times | November 02, 2009
Array BioPharma Reports Financial Results for the First Quarter of Fiscal 2010
...formulation in patients with solid tumors and three Phase 1b trials in combination with Xeloda ® ( capecitabine ), Taxotere ® ( docetaxel ) and Gemzar ® ( gemcitabine ), respectively. ARRY-380 - ErbB2 selective inhibitor for cancer : Patient...
In this article: Cancer, Revenue, Gemcitabine, Capecitabine, ErbB2, Glucose, and Docetaxel
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Centre Daily Times | October 21, 2009
Genzyme Reports Third-Quarter Financial Results
...expects these activities to continue throughout the fourth quarter. Third-quarter growth in this segment was also driven by Clolar ® ( clofarabine injection) and Mozobil® (plerixafor injection). Mozobil was launched in Europe following...
In this article: Genzyme Corp., Revenue, Fabrazyme, Clofarabine, FDA, Alemtuzumab, Fludarabine, Bayer, Trademark, and Tax
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Medical News Today | October 08, 2009
Genzyme Receives FDA Complete Response Letter For Clolar
... GENZ ) announced that the FDA provided a complete response letter regarding the company 's supplemental New Drug Application for Clolar ® ( clofarabine ) in previously untreated older adult patients with acute myeloid leukemia (AML) and at least...
In this article: Clofarabine, Genzyme Corporation, FDA, Cytarabine, Cancer, Accrual, Leukemia, Chronic myelogenous leukemia, Acute myeloid leukemia, and Nasdaq
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Reuters | October 06, 2009
UPDATE 1-FDA fails to approve Clolar in adults with AML
...or ongoing studies might be satisfactory. The company is conducting a late-stage trial comparing Clolar , known generically as clofarabine , in combination with the chemotherapy cytarabine to cytarabine alone in relapsed and refractory...
In this article: Genzyme, Clofarabine, FDA, Cytarabine, Acute myeloid leukemia, Leukemia, Acute lymphoblastic leukemia, and U.S.
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Reuters | September 01, 2009
U.S. panel rejects Genzyme leukemia drug study
...adults with AML. Genzyme needs FDA clearance, however, to market the drug specifically for the adults. The drug's generic name is clofarabine. JP Morgan analyst Geoffrey Meacham said the panel vote was "an incremental negative as it...
In this article: Genzyme Corp, Clofarabine, Leukemia, FDA, Cancer, U.S., Revenue, Acute myeloid leukemia, and University of Washington in Seattle
